新井 博文 ARAI HIROFUMI

学位

学歴

職歴

担当授業科目（学部）

基礎生物学　地球環境/短期履修, 基礎生物学　地域未来/短期履修, バイオ食品工学概論　地域未来（2020年度以前入学）, 食品化学　ﾊﾞｲｵ食品, バイオ食品工学実験II　ﾊﾞｲｵ食品, バイオ食品工学演習　ﾊﾞｲｵ食品, 食品栄養生理学　ﾊﾞｲｵ食品, 食品機能学　ﾊﾞｲｵ食品, 学術文献英語　ﾊﾞｲｵ食品, プレゼンテーション演習　ﾊﾞｲｵ食品, スポーツ工学　ﾊﾞｲｵ食品, スポーツ工学　地域ﾏﾈ, 地球環境工学入門/短期履修, 地域未来デザイン工学入門/短期履修, コース概論　地域未来, 地域未来デザイン工学入門　地域未来（2020年度以前入学）

担当授業科目（大学院）

生命科学特論I　応用化学, バイオ食品工学特論II　応用化学

専門分野

食品機能学, 栄養生理学

研究テーマ

培養細胞を用いた食品成分のアレルギー抑制作用評価, 培養細胞を用いた食品成分の炎症抑制作用評価, 培養細胞を用いた食品成分の生体酸化ストレス抑制作用評価

研究内容キーワード

機能性食品, 生活習慣病, アレルギー, 炎症, アテローム性動脈硬化症, 活性酸素, 酸化ストレス, 免疫細胞, ポリフェノール, 生薬, ハマナス, シーベリー, アロニア, ハスカップ

所属学会

日本フードファクター学会, 日本農芸化学会, 日本食品科学工学会, 日本栄養・食糧学会, 日本酸化ストレス学会, 日本水産学会

学術論文

論文名／掲載誌名等		掲載年月
Peroxyl radical scavenging activity of caffeic acid and its related phenolic compounds in solution Biosci. Biotech. Biochem., 57, 7, 1204-1205		1993-07
Lipid content and fatty acid composition of phospholipids in white-fresh fish species Fish. Sci., 60, 2, 177-184		1994-04
Effect of d-α-tocopherol analogues on lipoxygenase-dependent peroxidation of phospholipid-bile salt micelles Lipids, 30, 2, 135-140		1995-02
Coulometric detection in high-performance liquid chromatographic analysis of cholesteryl ester hydroperoxides Free Radic. Biol. Med., 20, 3, 365-371		1996-06
Reactivity of mammalian 15-lipoxygenase with phospholipids in large unilamellar liposomes Biochem. Biophys. Res. Commun., 228, 3, 675-682		1996-11
Coulometric electrochemical detection of phospholipid hydroperoxides by high-performance liquid chromatography Biosci. Biotech. Biochem., 61, 1, 191-193		1997-01
Oxidative modification of apolipoprotein E in human very low density lipoprotein and its inhibition by glycosaminoglycans Arch. Biochem. Biophys., 367, 1, 40186		1999-01
Distribution of muscular glutathione in fish and shellfish Fisheries Sci., 65, 1, 329-330		1999-04
VLDLの酸化とグリコサミノグリカンによる抑制 微量栄養素研究, 16, 153-158		1999-05
Electrophoretic analysis of oxidative modification of apolipoprotein E in very low density lipoprotein from fresh human plasma Electrophoresis, 20, 7, 1418-1424		1999-06
Phosphatidylcholine levels and their fatty acid compositions in teleost tissues and squid muscle Comp. Biochem. Physiol. [B], 124, 1, 109-116		1999-09
VLDL中のアポリポプロテインEの酸化とその抑制 生物物理化学, 44, 271-275		2000-05
Lipoproteins modulate growth and differentiation of cultured human epidermal keratinocytes Electrophoresis, 23, 2, 161-166		2002-01
Inhibition of heat-induced phosphorylation of stathmin by a bioflavonoid, quercetin Electrophoresis, 23, 4, 670-673		2002-02
Electrophoretic studies on the phosphorylation of stathmin and mitogen-activated protein kinases in neuronal cell death induced by oxidized very-low-density lipoprotein with apoE Electrophoresis, 23, 7, 998-1004		2002-04
A signaling pathway by a new synthetic lipid A analog, ONO-4007, in RAW 264.7 cells Anti-Cancer Drugs, 13, 10, 1069-1075		2002-12
Effects of α-tocopherol on oxidative modification of apolipoprotein E in human very-low-density lipoprotein Biosci. Biotechnol. Biochem., 67, 2, 402-405		2003-02
Formation of Nε-(hexanonyl)lysine in oxidized human very-low-density lipoprotein J. Electrophoresis, 48, 1, 37-40		2004-02
Effect of L-ascorbic acid on the oxidative modification of apolipoprotein E in human very-low-density lipoprotein J. Nutr. Sci. Vitaminol., 50, 1, 66-68		2004-02
Colocalization of apolipoprotein AI in various kinds of systemic amyloidosis J. Histochem. Cytochem., 53, 2, 237-242		2005-02
Effect of bicarbonate on iron-mediated oxidation of low-density-lipoprotein Proc. Natl. Acad. Sci. U.S.A., 102, 30, 10472-10477		2005-07
Characterization of trans eicosapentaenoic acid isomers: oxidative stability and anti-inflammatory activities J. Oleo Sci., 54, 9, 505-512		2005-08
Effect of ascorbate on acrolein modification of very-low-density lipoprotein and uptake of oxidized apolipoprotein E by hepatocytes Biosci. Biotechnol. Biochem., 69, 9, 1760-1762		2005-09
Protein oxidation by the cytochrome P450 mixed-function oxidation system Biochem. Biophys. Res. Commun., 338, 1, 432-436		2005-12
天然イサキの死後変化に及ぼす保存温度の影響 日本食品化学学会誌, 14, 1, 40184		2007-02
養殖ブリのヤケ肉発生に伴うATPase活性からみた筋原線維タンパク質の変化について 日本食品化学学会誌, 14, 1, 40370		2007-02
アオリイカ外套筋の白濁に及ぼす保存温度の影響 日本水産学会誌, 74, 5, 856-860		2008-04
Suppression of color degradation of yellowtail dark muscle during storage by simultaneous dietary supplementation of vitamin C and E Fish Sci., 75, 499-505		2009-04
Effects of dietary fish protein on serum and liver lipid concentrations in rats and the expression of hepatic genes involved in lipid metabolism J. Agric. Food Chem., 57, 19, 9256-9262		2009-10
海産物由来抗酸化物質 食品・食品添加物研究誌, 215, 31-37		2010-02
Effect of dietary protamine on lipid metabolism in rats Nutr. Res. Pract., 4, 462-469		2010-04
Effect of phospholipid n-3 polyunsaturated fatty acids on rat lipid metabolism Eur. J. Lipid Sci. Technol., 112, 5, 537-544		2010-05
Effect of simultaneous intake of fish protein and fish oil on cholesterol metabolism in rats fed high-cholesterol diets The Open Nutraceuticals Journal, 4, 12-19		2011-02
Fish protein decreases serum cholesterol in rats by inhibition of cholesterol and bile acid absorption J. Food Sci., 76, 4, H116-H121		2011-05
Fish protein hydrolysates affect cholesterol metabolism in rats fed non-cholesterol and high-cholesterol diets J. Med. Food, 15, 3, 299-306		2012-03
Combination effect of phospholipids and n-3 polyunsaturated fatty acids on rat cholesterol metabolism Food Sci. Biotechnol., 21, 5, 1335-1342		2012-10
Effect of combination of dietary fish protein and fish oil on lipid metabolism in rats J. Food Sci. Technol., 50, 2, 266-274		2013-04
養殖ブリ属（ブリ、カンパチおよびヒラマサ）血合筋の保存中における肉色変化の比較 日本水産学会誌, 79, 3, 416-421		2013-05
Oxidative modification of lipoproteins Subcell. Biochem., 77, 103-114		2014-01
Effect of treatment temperature on the biocompatibility and mechanical strength of hydroxyapatite coating formed on titanium using calcium phosphate slurry Surf. Coat. Tech., 239, 185–190		2014-01
Effects of soybean isoflavones on the release of chemical mediators from rat peritoneal exudate cells by allergic reaction in vitro Food Sci. Technol. Res., 20, 3, 725-730		2014-07
Effect of sterilization and water rinsing on cell adhesion to titanium surfaces Appl. Surf. Sci., 311, 498–502		2014-08
Response of osteoblast-like MC3T3-E1 cells on bioactive titanium fabricated by a chemical treatment process using a calcium-phosphate slurry J. Biomed. Mater. Res. Part A, 102, 11, 3838–3845		2014-11
Effect of bean extract of yabumame (Amphicarpaea bracteata (L.) Fernald subsp. edgeworthii (Benth.) H.Ohashi) on low-density lipoprotein oxidation in vitro Food Sci. Technol. Res., 21, 4, 589-596		2015-07
Electrolyte effects on the surface chemistry and cellular response of anodized titanium Appl. Surf. Sci., 349, 911-915		2015-09
Salmon protamine decreases serum and liver lipid contents by inhibiting lipid absorption in an in vitro gastrointestinal digestion model and in rats J. Food Sci., 80, H2346-H2353		2015-10
Porcine hemoglobin promotes lipid excretion to feces more strongly than globin protein in rats Food Science and Biotechnology, 25, S1, 107-112		2016-04
Surface chemistry and osteoblast-like cell response on a titanium surface modified by a focused Nd:YAG laser Surface and Coatings Technology, 309, 220-226		2017-01
Effects of oolonghomobisflavan A on oxidation of low-density lipoprotein Bioscience, Biotechnology, and Biochemistry, 81, 8, 1569-1575		2017-05
A new method to evaluate anti-allergic effect of food component by measuring leukotriene B4 from a mouse mast cell line Cytotechnology, 70, 1, 177-184		2018-02
カキ肉エキスの給餌によるラットの盲腸内細菌叢の変化 微量栄養素研究, 35, 41-46		2018-12
ロイコトリエンを指標としたポリフェノール類の抗アレルギー活性評価 日本ポリフェノール学会雑誌, 8, 1, 18-21		2019-03
New isoflavone glucosides in yabumame (Amphicarpaea bracteata (L.) Fernald subsp. edgeworthii (Benth.) H.Ohashi var. japonica (Oliv.) H.Ohashi) and their effect on leukotriene B4 production in mast cells Journal of Natural Medicines, 75, 1, 28-36		2021-01
Echinacea purpurea water extracts suppress the release of chemical mediators from mast cells Bioscience, Biotechnology, and Biochemistry, 85, 4, 931-940		2021-04
ニンニク'北海道在来'の摂取によるアポリポプロテインE欠損マウスの動脈硬化進展抑制効果 日本健康医学会雑誌, 30, 1, 76-82		2021-04
Evaluation of Hesperidin on Sausages Stuffed in a New Modified Casing during Long-Term Storage - A Preliminary Study Sustainability, 14, 15, 9071		2022-07
Evaluation of pH in Sausages Stuffed in a Modified Casing with Orange Extracts by Hyperspectral Imaging Coupled with Response Surface Methodology Foods, 11, 18, 2797		2022-09
Hyperspectral Imaging Combined with Chemometrics Analysis for Monitoring the Textural Properties of Modified Casing Sausages with Differentiated Additions of Orange Extracts Foods, 12, 5, 1069		2023-03
Estimating Moisture Content of Sausages with Different Types of Casings via Hyperspectral Imaging in Tandem with Multivariate Applied Sciences, 13, 5300		2023-04
Fermentation of soybeans with Pleurotus cornucopiae and Pleurotus ostreatus increases isoflavone aglycones, total polyphenol content and antioxidant activity Mycoscience, 64, 156-165		2023-09
Effect of Polyphenols in Sea Buckthorn Berry on Chemical Mediator Release from Mast Cells Preventive Nutrition and Food Science, 28, 3, 335-346		2023-09
Assessment of adenosine triphosphate content in sausages stuffed in different modified casing treatments added with orange extracts, utilising hyperspectral imaging combined with multivariate analysis Frontiers in Nutrition, 11		2024-03
Isolation of two flavonol glycosides from Rosa rugosa pollen and their anti-inflammatory effect in lipopolysaccharide-stimulated macrophages Food Science and Technology Research, 30, 3, 431		2024-04

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